Emphysema chest tightness, shortness of breath can be treated with bronchodilators, glucocorticoids, expectorants, antibiotics and so on. 1. Bronchodilators: can be targeted to relieve shortness of breath, wheezing symptoms, commonly used drugs are salbutamol, ipratropium bromide, aminophylline and so on. 2. Glucocorticosteroids: can reduce the frequency of acute exacerbations and improve the quality of life, commonly used drugs include budesonide, etc. 3. Expectorant drugs: emphysema can cause chest tightness and shortness of breath due to more sputum, which can be applied to those who can not cough up sputum easily, and commonly used drugs include aminobromine hydrochloride, carbocysteine, and so on. 4. Antibiotics: combined lung infection should be based on the location of the patient common pathogenic bacteria and their drug sensitivity to actively choose antibiotic treatment, common drugs are amoxicillin, cefuroxime, levofloxacin, and so on. The choice and application of specific drugs need to be based on medical advice, if the patient suddenly chest tightness and breathlessness, be alert to the possibility of pneumothorax, it is recommended to go to the hospital in a timely manner to clarify the cause of the disease, under the guidance of the doctor for treatment.