According to the results of related studies, among the factors affecting the progression of IgA nephropathy, the combination of hypertension in patients with IgA nephropathy is one of the independent risk factors. Hypertension is both a risk factor for the progression of IgA nephropathy and an important indicator of poor prognosis. Therefore, for patients with IgA nephropathy to effectively delay the progression of IgA nephropathy, it is important to adopt effective diagnostic methods for early detection and control of the disease. About 40% of patients with IgA nephropathy are combined with hypertension. If these patients do not receive timely and effective antihypertensive treatment and the hypertensive state lasts too long, it will further aggravate the proteinuria and make the glomerular filtration rate decrease. Some studies have shown that for every 10 mmHg increase in mean arterial pressure, the glomerular filtration rate decreases by an additional 2 ml/min per year, and good blood pressure management can reduce the risk of entering dialysis or having cardiovascular events in patients with IgA nephropathy. Clinically, IgA nephropathy patients with hypertension have significantly worse blood creatinine levels, blood uric acid, 24-hour urine protein quantification and other clinical indicators than IgA nephropathy patients with normal blood pressure. In terms of pathological manifestations, patients with IgA nephropathy with hypertension had more severe glomerulosclerosis, tubular atrophy, interstitial inflammatory cell infiltration, interstitial fibrosis and small vessel lesions than patients with IgA nephropathy with normal blood pressure. Active blood pressure control is important to improve the clinical prognosis of IgA nephropathy.