Premature ejaculation due to chronic prostatitis is usually curable. Inflammation of the urinary system is one of the common causes of premature ejaculation, such as nephritis, cystitis, prostatitis, urethritis, etc. When the primary disease is cured, the secondary premature ejaculation due to it may be better improved, or even completely return to normal. Chronic prostatitis requires standardized and individualized treatment. Bacterial prostatitis is mainly based on the rational use of antibiotics (e.g., cefixime, etc.), while non-bacterial prostatitis is mainly based on the use of non-steroidal anti-inflammatory drugs (e.g., ibuprofen, etc.) and other drugs. Patients should pay attention to develop a light diet, maintain hygiene, moderate sex life, pay attention to keep warm and other good lifestyle and habits in daily life.