1. Gastroflucan is prohibited in the case of upper gastrointestinal bleeding, and the pharmacopoeia only has the usage of intramuscular injection, not intravenous injection or intravenous drip. 2, gastric ulcer patients are prohibited pethidine. 3, gastrointestinal motility drugs (commonly used gastrofacial. morpholine. Mosapride) should not be used in combination, the extrapyramidal reactions increase. 4, gastrointestinal drugs should not be used in combination with anticholinergic drugs, the role of reduced. 5, gastrointestinal drugs should not be used in combination with acidulants. Aluminum is used in combination. 6, gastrointestinal drugs to promote gastrointestinal motility, affecting the absorption of the above two drugs, if combined at least 1 hour between dosing time. 6.Cimetidine should not be used in combination with aluminum thioglycollate. 7, aluminum thioglycollate needs to be hydrolyzed by gastric acid to complex with pepsin and play anti-ulcer effect, while cimetidine inhibits gastric acid secretion, thus reducing the effectiveness of aluminum thioglycollate. 8, bismuth potassium citrate should not be used in combination with aluminum hydroxide. 9, bismuth potassium citrate needs to form bismuth oxide colloid under acidic conditions of gastric juice to form a protective film, while aluminum hydroxide increases the ph value in the stomach, causing the effect of bismuth potassium citrate to be weakened. 10, cisapride is prohibited for people with hypokalemia. 11, such as cirrhotic patients prone to hypokalemia, sometimes combined with cisapride due to poor gastrointestinal motility, but hypokalemia with cisapride can cause serious arrhythmias. 12. Cisapride is contraindicated in sick sinus node syndrome. 13. Cisapride may delay cardiac repolarization and may cause prolongation of the Q-T interval. Syncope and severe arrhythmias, bradycardia is prohibited with cisapride. 14, live bacteria preparations should not be combined with antibiotics and astringents. 15, antibiotics to make live bacteria preparations (such as lactase raw. (Lizhu enteral) inactivation, astringent (such as ellagitin. Bismuth subcarbonate) can be adsorbed live bacteria, reducing the effectiveness of the drug.