Mis-cut parathyroid glands can be seen in thyroid surgery, and a series of clinical manifestations caused by low blood calcium can occur after mis-cutting, and the clinical symptoms mostly appear after the operation, with varying degrees of severity. After the parathyroid glands are cut, the blood calcium will be lowered, and most of the patients will feel numbness in the face, around the mouth or limbs at the beginning, and in severe cases, facial muscle spasm and hand and foot spasm with pain will occur, which will happen several times a day. In critical cases, laryngeal and diaphragmatic spasms can be seen, which may cause death by asphyxiation. It can be slightly judged by the above manifestations. In order to protect the parathyroid glands and minimize the occurrence of postoperative hand and foot spasms, intraoperative care must be taken to carefully search for and preserve them. When the thyroid body is removed, the dorsal portion is preserved as much as possible, and the thyroid vessels are ligated in the immediate vicinity of the thyroid gland to protect the blood supply to the parathyroid glands. The excised thyroid specimen may also be carefully examined and the parathyroid glands may be autotransplanted if found. Nonetheless, patients with hypocalcemia need to be actively treated and closely monitored under medical supervision to avoid exacerbation of the condition.