The main causes of persistent intercostal pain in myofasciitis include physiologic factors and pathologic factors. 1. Physiological factors: mainly due to fatigue injury, prolonged ambulatory work and other factors. Intercostal fascia is made of connective tissues that cross longitudinally and transversally, due to the small number of transverse fibers, it is easy to be damaged when the cutaneous nerve is stimulated, which leads to the imbalance of bilateral intercostal muscle force, causing strain on one side of the intercostal fascia, thus causing fasciitis of the intercostal area. 2. Pathological factors: Most of the injuries to the ribs, costal cartilage and intercostal nerves cause aseptic inflammation of the intercostal muscles and fascia. Commonly, such as rib fracture, costochondritis, infection, etc. Pathological factors can cause increased intercostal muscle tension, or even intercostal muscle spasm, resulting in myofascial fatigue compensation, aseptic inflammation. Myofasciitis intercostal persistent pain may also have other causes, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.