Adults with anal itching may have worms, may be pinworm infection caused by rapsis, or there may be no worms, it is external hemorrhoids, perianal eczema and other diseases caused. 1. Pinworm disease: pinworm disease is mainly caused by pinworm infection, patients will appear around the anus or perineum itching, nausea, vomiting and other symptoms. If the patient is infected with pinworms, the anal itching is a manifestation of the presence of worms. 2. External hemorrhoids: external hemorrhoids are mainly due to venous thrombosis, perianal skin inflammation and other factors, the patient’s main symptoms for pain, itching, foreign body sensation, anal swelling and blood in the stool. If external hemorrhoids cause anal itching, there is no worm. 3. Perianal eczema: the etiology of perianal eczema is not clear, considering a variety of external factors as well as internal factors. Patients will appear perianal itching, erythema, blisters and flaking and other symptoms, if the perianal eczema caused by anal itching, there is no worm. When patients have symptoms of anal itching, there is not necessarily a worm, but may also be caused by pruritus ani. It is recommended that patients seek timely medical examination to clarify the cause of the disease, as soon as possible to follow the medical advice to give treatment, to avoid causing delays in the condition.