For knee gout pain relief methods, you can choose oral drugs, topical drugs for pain relief, but also through systemic intravenous administration, or local puncture in the joint cavity to relieve pain, as follows: 1, oral administration: the most commonly used is colchicine and non-steroidal anti-inflammatory painkillers, commonly used non-steroidal anti-inflammatory painkillers are mainly loxoprofen sodium, meloxicam, celecoxib, etoricoxib tablets, etc. 2, topical drugs: mainly flurbiprofen Bab cream, piroxicam patch, etc., are commonly used non-steroidal anti-inflammatory painkillers. 2, topical drugs: mainly flurbiprofen babu cream, piroxicam patch, etc., are commonly used non-steroidal anti-inflammatory painkillers. 3, systemic intravenous administration: if oral and topical preparations are less effective, you can choose intravenous administration, intravenous administration is often chosen glucocorticoids, such as methylprednisolone. 4, intra-articular cavity local puncture administration: if the knee gout and If there is a large amount of joint cavity fluid, you can also choose joint cavity puncture to extract the fluid, local intra-articular injection of compound betamethasone injection or tretinoin, to carry out anti-inflammatory and pain relief treatment.