Traumatic infection of meningioma needs to be analyzed specifically according to the site of infection and the degree of infection, and anti-infection treatment is usually carried out. 1. Meningioma is a kind of primary intracranial tumor, mostly benign, with no obvious symptoms in the early stage, and symptoms appearing in the later stage with the enlargement and compression of the tumor, which is mainly treated by surgery and supplemented by radiotherapy. When the traumatic infection of meningioma occurs, it is necessary to consult doctor in time and carry out reasonable anti-infection treatment for the infected area. 2. For acute infection, it is necessary to treat the wound and remove the cause of the disease in time, such as open wound infection, should perform debridement, and use isotonic saline gauze to drain the pus and promote the growth of granulation tissue. In addition, infected wounds also require the use of antimicrobial drugs according to the injury and the degree of infection. 3. There are many kinds of antibacterial drugs, such as penicillin, cephalosporin, β-lactam, etc., which need to be selected under doctor’s guidance with full combination of personal situation. Traumatic infection of meningioma needs to be treated in the hospital under the guidance of physicians, so as to avoid delaying the condition and causing adverse effects.