The high fever is caused by viral or bacterial invasion. When these symptoms occur, the patient should consult the doctor in time, complete the relevant examinations, and follow the doctor’s instructions to give anti-infective, antipyretic and detoxifying medication. Nasal congestion and high fever are common symptoms of cold and flu. If these symptoms occur due to cold and flu, the patient should consult the doctor in time, complete the blood test, bacterial culture and other tests to clarify whether it is a simple viral infection or a combined or secondary bacterial infection, so as to provide more accurate treatment. If there is no evidence of bacterial infection, antiviral treatment is not necessary, and for immunocompromised people, antiviral drugs such as oseltamivir can be given; if there is a combined or secondary bacterial infection, appropriate antibiotics should be used for treatment. Common ones are cefoperazone and amoxicillin, etc. Oral, intramuscular, or infusion treatment is often chosen according to the severity of the disease. When the patient has a high fever, the effect of simple physical cooling is not good, you can take oral ibuprofen and other fever-reducing drugs under the guidance of the doctor, and assisted by warm water baths and other physical cooling treatment. Patients with colds and flu with the above symptoms, medication should strictly follow the instructions of the doctor, actively cooperate with the treatment, drink more water, more rest, eat more fresh fruits and vegetables, avoid spicy and stimulating food.