Blackheads, also known as open pimples, may be caused by increased hormone secretion, increased cortical secretion, and massive reproduction of Propionibacterium acnes, etc. The main methods to remove blackheads are general treatment, medication, and medical aesthetic treatment. 1. General treatment: Wash your face with lukewarm water or high safety detergents to avoid oil secretion and keep your face clean and dry. Do not eat spicy, greasy, stimulating food, drink more water, eat more fresh fruits and vegetables, regular work and rest without staying up late. Don’t squeeze blackheads with your hands, and don’t stimulate pores with too hot water or irritating skin care products. 2. Medication: Adapalene gel, benzoyl peroxide gel, azelaic acid cream and other drugs can be used externally, if necessary, with oral isotretinoin soft capsules to treat. 3. Medical treatment: You can use fruit acid peeling or salicylic acid peeling and other medical means to promote the aging of the stratum corneum off, so as to open the pores to remove blackheads. You can also do photorejuvenation to solve the problem of blackheads. When suffering from blackheads, it is recommended not to use drugs or skin care products to remove them on your own, you should go to the hospital in time, and the doctor will carry out targeted treatment according to the specific situation. Drugs need to be used in accordance with medical advice.