High urinary microalbumin needs to be identified as the cause of the disease and targeted treatment. If it is caused by physiological factors, such as strenuous exercise, no special treatment is needed; if it is caused by pathological factors such as glomerulonephritis, hypertensive nephropathy, diabetic nephropathy, etc., it is necessary to actively treat the primary disease, and give general treatment, hormone and other medications. 1. Physiological factors: for people who are nervous or have strenuous exercise, high urinary microalbumin may occur, which can turn into negative after resting, and no special treatment is needed. 2. Pathologic factors: (1) Glomerulonephritis: glomerulonephritis may cause the destruction of glomerular basement membrane structure and high urine microalbumin. Sartans or prilosec can be preferred, such as irbesartan, captopril, etc. Glucocorticosteroids such as prednisone and other immunosuppressants need to be applied for treatment when necessary. At the same time, pay attention to rest during the treatment, limit salt intake and so on. (2) Hypertensive nephropathy: Long-term hypertension will also affect the kidneys, which can cause high urinary microalbumin. The medicines can be applied are sartans or prilosec, such as irbesartan, captopril, etc. to lower the blood pressure and reduce the urinary protein. (3) Diabetic nephropathy: Diabetic nephropathy can lead to high urine microalbumin, actively control the blood sugar level, can be applied to lower glucose treatment such as acarbose, gliclazide, etc., and insulin can be applied when necessary. At the same time, moderate exercise, limit the intake of high-sugar food. If the patient found that the urine microalbumin is elevated, it is recommended to go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.