After a needle-stick injury, squeeze from proximal to distal to squeeze as much blood out of the injury as possible. At the same time, wash the contaminated skin with soapy water and running water, disinfect with 75% alcohol or iodophor after rinsing, and exposed mucous membranes should be rinsed with saline. In case of occupational exposure, after local treatment, report to the relevant departments and personnel in accordance with the occupational exposure process of each unit, and immediately retain the blood specimen of the person who has been pricked by the needle for examination of hepatitis B, hepatitis C and HIV. Understand the patient’s situation, take the patient’s relevant examination, if it is determined that the patient is a patient with infectious disease, can start anti-infectious disease treatment, and review the relevant examination after three months.