Is medication for facial spasm effective? Generally facial muscle spasm will be used at the beginning of the drug to relieve and control the condition, but whether the actual disease can be relieved depends on the degree of disease onset. Facial muscle spasm is a condition of involuntary twitching of the half side of the face, twitching is often paroxysmal and irregular, varying degrees, can be aggravated by fatigue, mental tension. The disease is most prevalent after the age of 40, with the majority of female patients. Eyelid or eyelid fluttering, twitching at the corners of the mouth or twitching in other parts of the face can affect the patient’s image and bring social problems to the patient. In the treatment of facial muscle spasm, the most effective drug is carbamazepine, followed by oxcarbazepine, phenytoin sodium, etc. The principle of botulinum toxin type A treatment is to inhibit the release of acetylcholine from the presynaptic membrane of peripheral motor nerve endings, causing relaxation paralysis of muscles, so that the muscle spasm disappears temporarily, but will soon relapse, and long-term injection, easy to damage the nerves, resulting in facial paralysis and other sequelae. The pathological mechanism of Chinese medicine for facial muscle spasm is unclear, and the effect is not obvious. While methylcobalamin tablets and vitamin B1 are anti-inflammatory, such as neuritis and gingivitis, etc. Patients are advised to treat facial muscle spasm best to go to a tertiary hospital neurology department for regular treatment. If the patient has frequent episodes of facial muscle spasm and takes carbamazepine drug with high dose and unsatisfactory effect, he can hang neurosurgery and ask neurosurgery experts to evaluate the possibility of surgical treatment. Generally, the most commonly used surgical procedure is microvascular decompression because it is found that about 80% to 90% of patients’ pathogenesis is caused by vascular compression of the facial auditory nerve. Microvascular decompression treatment is the application of microsurgical techniques to remove the vascular compression and then place decompression materials between the nerve and the blood vessels to achieve the disappearance of facial pain after surgery, with a cure rate of more than 96%. Moreover, microvascular decompression treatment is minimally invasive and safe, does not damage the nerve, and can preserve the integrity and functionality of the facial nerve. The effect of general drug treatment is not very obvious, so it is recommended that patients should go to the hospital for treatment and take a reasonable nutritional diet on weekdays, forbid spicy and stimulating food as well as high heat and cold food, and do not drink alcohol, so as to benefit the early recovery of facial muscle spasm.