If palpitations always occur at night while sleeping, patients are advised to take oral beta-blockers, such as bisoprolol or metoprolol, to help prevent myocardial ischemia, slow down the heart rate, and inhibit sympathetic excitability. Relatively speaking, it is effective for the treatment of atrial premature. However, if the drug is to be taken, it must not be present in the presence of hypotension, bronchial asthma, and chronic obstructive pulmonary disease, which may trigger respiratory distress and hypotension. If the patient sleeps with palpitations, which are caused by psycho-psychological factors, it is recommended to use a sleep improving, sedative drugs, such as clonazepam, eszopiclone or dexrazoxane. These drugs are relatively are also very good choices to help improve the patient’s palpitations, and it is also recommended that patients can combine psychological relief if necessary.