There are no new medications that specifically treat irritable bowel syndrome. Irritable bowel syndrome can be treated with drugs that regulate gastrointestinal dynamics, and if accompanied by symptoms of anxiety and depression, antidepressant and anti-anxiety drugs are also needed. 1. Drugs to regulate gastrointestinal dynamics: patients with irritable bowel syndrome often have diarrhea and constipation, and can apply drugs to regulate gastrointestinal dynamics, such as trimethoprim, mosapride, itopride and so on. 2. Antidepressant and anti-anxiety drugs: antidepressant and anti-anxiety drugs can be used for those with obvious mental symptoms. Tricyclic antidepressant amitriptyline can be used for patients with diarrhea; 5-hydroxytryptamine reuptake inhibitor paroxetine or citalopram can be used for patients with constipation. 3. Intestinal microecological agents: such as bifidobacteria, lactobacillus, caseinate bacteria and other preparations, can correct intestinal flora imbalance, diarrhea, abdominal distension has a certain effect. It is recommended that patients with irritable bowel syndrome go to the hospital in a timely manner, follow the doctor’s instructions for drug treatment, and do not use drugs privately.