The first thing to reassure people is that leukemia is not a genetic disease. So, what is a genetic disease? A hereditary disease is a disease that is caused by a genetic problem in the body and manifests itself in families. If the same disease occurs in every generation, it is called a “dominant genetic disease”; if it does not occur in every generation, it is called a “recessive genetic disease”; if it is also related to gender, it is called a “sex-linked genetic disease”. If it is also related to gender, it is called a “sex-linked genetic disorder”. You may have seen “albinism”, that is, hair, eyebrows, skin are white, especially afraid of the sun, this disease is dominant genetic disease. There is also “six fingers”, that is, the hand (or foot) has six fingers, this is also a dominant genetic disorder. Some parents may have seen a family with several people with leukemia or other neoplastic diseases. Yes, many neoplastic diseases (including leukemia) are not genetic, but they are genetically predisposed. For example, with the same exposure to radiation and air pollution, some people in some families are more susceptible to leukemia than others, but without these predisposing factors, no one would have developed leukemia. This is just different from hereditary diseases, which develop regardless of the conditions. Parents often ask: What tests do parents need to do if they still want a second child? Because there is no specific method to check for genetic susceptibility, there is no specific test for parents. With the completion of the Human Genome Project, it will be possible to test for genetic susceptibility in the future when a convenient, fast and affordable method is developed that sequences all of the genes in each person. Therefore, it is possible for parents with leukemia to have a second child, but the key is to be in good physical and mental condition when preparing for conception, and to avoid infections and exposure to harmful substances during the pregnancy in order to have a healthy child. In fact, we have many parents of children with leukemia who have had healthy second children.