Wake up in the morning soreness on both sides of the waist to consider and lumbar muscle strain, lumbar disc herniation, ankylosing spondylitis, urinary system diseases and so on. 1. Lumbar muscle strain: If a long time a posture, such as sedentary or standing for a long time easily caused by muscle strain on both sides of the lumbar, lumbar pain on both sides of the waist, appropriate activities lumbar symptoms can be alleviated, usually pay attention to strengthen the lumbar back muscle exercise. 2. Lumbar disc herniation: lumbar degeneration, nucleus pulposus protrudes into the spinal canal through the annulus fibrosus and compresses the nerves, which can lead to lumbar pain and radiates to the lower limbs, which can be clearly diagnosed by MRI. 3. Ankylosing spondylitis: pain around the lumbar vertebrae, limitation of lumbar spine activities, morning stiffness, which can be found through radiography. 4. Urological diseases: such as urinary tract infections, nephritis and other diseases, can also lead to symptoms of soreness on both sides of the waist. Waking up in the morning with soreness on both sides of the waist has a complex etiology, and it is recommended to go to the hospital in a timely manner.