Patient: I am a female, 45 years old, who underwent a modified radical mastectomy for breast cancer on July 22. She was diagnosed with invasive ductal carcinoma of the breast with lymphocytic infiltration grade II, lymph nodes without cancer 0/12, ER(-) PR(-), CerBb2(-), Ki-67>40%. Three chemotherapy sessions had been performed after radical mastectomy. The first chemotherapy was with epirubicin and paclitaxel, and then the second and third chemotherapy were changed to cyclophosphamide and paclitaxel due to frequent sequential premature beats. Will this change in dosing affect the efficacy of the treatment? How many cycles of chemotherapy are needed in this case? Doctor: 3 cycles have been administered and the switch to paclitaxel plus platinum can be done for 3 to 4 cycles. Because the prognosis of triple negative breast cancer is not too good. The good thing is that there is no metastasis in the axillary lymph nodes, I don’t know the size of the tumor? Ki-67>40% means positive Ki-67 expression, the higher the percentage of positive means the malignancy of breast cancer tumor cells, active cell proliferation, so the tumor grows fast, invasive, high chance of metastasis and poor prognosis. However, in this case, Ki67 can also be used as an indicator of breast cancer chemotherapy sensitivity, which means that the larger the indicator is, the more sensitive the tumor is to chemotherapy and the better the chemotherapy effect. So sometimes a bad indicator does not have to be bad. Patient: Thank you very much! The tumor size is 1.9*1.5*1.1, I wonder what other treatment is recommended in this case? How else do I need to treat this situation after the chemotherapy is finished besides regular review? Do I need to use some oral medication? In addition, I feel numbness in my feet recently, is this a reaction to chemotherapy? Doctor: After chemotherapy, apart from regular check-ups, you can take some oral medicine to help you. The numbness of the feet is a side effect of paclitaxel, so you can take some vitamin B drugs, vitamin B1, methylcobalamin tablets and other drugs orally. In the next chemotherapy, you can inject adenosine cobalamin or vitamin B1 intramuscularly to have a preventive effect. Patient: What should I do to reduce the chance of recurrence and metastasis? What do I need to do for future treatment? Doctor: 1.Regular review 2.Chinese herbal remedial treatment 3.Immune function treatment for a period of time after chemotherapy, and then do 3 months of treatment every year. 4.Appropriate exercise. 5, happy mood! 6, regular life, regular diet. Nutritious, often eat fruits and fresh vegetables rich in vitamins. Consume more soy products. Patient: Immune function treatment and 3 months of treatment per year from which and how to treat? Doctor: The drugs to increase immune function are ribonucleic acid, thymidine, interleukin 2, etc. It is beneficial to do 3 months of treatment per year with drugs that increase immune function.