The clinical significance of elevated interleukin-8, or interleukin-8, is to suggest that an individual may have inflammatory diseases such as hepatitis, rheumatoid arthritis, psoriasis, and other diseases such as coronary heart disease. Interleukin-8 is a cytokine, mainly produced by macrophages, capable of transmitting information, activating and regulating immune cells, and mediating the activation and proliferation and differentiation of T cells and B cells. 1. When there are inflammatory diseases such as hepatitis, rheumatoid arthritis, psoriasis, etc., the body may generate a large number of leukocytes or other immune factors, which induce an increase in interleukin-8 to resist pathogens. 2. In addition to inflammatory diseases, other diseases such as coronary heart disease, myocardial infarction, chronic obstructive pulmonary disease, etc., can also cause interleukin-8 to increase. When the test value of interleukin-8 is elevated, other tests, such as blood test, urine test, liver function, etc., should be carried out under the advice of the doctor in order to clarify the cause of the disease and to carry out treatment under the guidance of the doctor.