Late stage colds with excessive phlegm and nasal discharge can be treated symptomatically with decongestants, antihistamines, cough and phlegm medications, and antibiotics if there is evidence of bacterial infection. Colds are often caused by cold or decreased resistance, mostly viral infections, often with nasal congestion, sneezing, runny nose, sore throat and cough. Except for influenza, antiviral medication is generally not needed. If the symptoms are mild, general treatment such as rest and drinking plenty of water can be given. If the symptoms are severe, symptomatic treatment can be given. If the patient has a runny nose, decongestants such as oxymetazoline and ephedrine can be given to improve the symptoms, or antihistamines such as cetirizine can be given to improve the symptoms. If there is a lot of phlegm, drugs such as Ambroxol and Bromhexine can be given to relieve cough and resolve phlegm. If yellow sputum or yellow nasal mucus is present, antibiotics such as cefaclor, azithromycin and levofloxacin tablets should be used. The sputum and snotty nose can also be caused by other diseases, if the patient’s symptoms are not relieved or aggravated, it is recommended to consult a doctor in time, under the guidance of the doctor for medication, so as not to delay the condition.