Prednisone, or prednisone acetate tablets, generally do not affect uterine fibroids. Prednisone acetate tablets, an adrenocorticotropic hormone drug with anti-inflammatory and anti-allergic functions, is mainly used in the treatment of allergic and autoimmune inflammatory diseases, such as connective tissue disease, systemic lupus erythematosus, vasculitis and so on. If the dose of prednisone acetate tablets is too large, it may cause diabetes, peptic ulcer and other diseases, and prolonged use will lead to skin atrophy, capillary dilatation, hyperpigmentation or secondary infection. Uterine fibroids are hormone-dependent tumors, whose growth is related to sex hormones and will not be affected by adrenocorticotropic hormone. And, there is no mention of adverse effects on uterine fibroids in the adverse effects that occur after taking prednisone acetate tablets. If you have uterine fibroids and need to take prednisone acetate for anti-inflammatory and anti-allergy treatment, you can take the medicine under the guidance of your doctor, and you should not self-administer or change the dosage or stop the medicine.