Right lateral paraventricular softening foci with gliosis means necrosis of brain parenchyma, old lesions. Cerebral softening foci are necrosis, liquefaction and resorption of brain tissue due to various causes, thus forming localized cystic cavities of varying degrees of severity, filled with cerebrospinal fluid, and manifesting as localized areas of low density on CT. The causes of cerebral softening foci include traumatic brain injury, cerebral infarction, cerebral hemorrhage, and ischemic-hypoxic encephalopathy. A common cause of right lateral paraventricular softening foci is cerebrovascular disease, and gliosis is inflammation and scarring of cells surrounding neurons in the brain. Softening foci with gliosis are generally suggestive of posterior phase lesions. If the examination has the above description, it is recommended to go to the hospital in time to clarify the etiology and intervene as early as possible to prevent recurrence.