The exact cause of Kawasaki disease in young children is still unknown, but it may be related to genetics, which may come from the mother or the father. In addition to the important relationship with bacterial or viral infections, studies have also shown that Kawasaki disease is also related to autoimmune factors, drugs, and environmental pollution (chemical irritation). This disease is more prevalent in boys than in women and is more likely to develop in late winter and early spring. It is one of the leading causes of heart disease in children and is not contagious.