Mycoplasma genitalium and Chlamydia humanum are mainly infected through sexual contact, but also through indirect contact. 1. Sexual contact: Mycoplasma genitalium and Chlamydia humanum are mainly transmitted through sexual contact, that is, having sex with patients and healthy carriers, resulting in cross-transmission, thus infecting Mycoplasma genitalium and Chlamydia humanum. 2. Indirect contact: it is possible to contact or eat the patient’s contaminated towels, bath towels, underwear, public toilets and other household items to cause cross-transmission, but also through public baths, swimming pools and other ways, indirect infection. Infected with Mycoplasma genitalium and Chlamydia humanum, both husband and wife should go to the hospital at the same time for examination and diagnosis, and have the disease to follow the doctor’s instructions for treatment.