Pulmonary isolation is one of the most common congenital pulmonary surgical disorders in children. With the development and advancement of prenatal ultrasonography, the vast majority of these cases can be diagnosed prenatally. Unlike cystic adenomatoid malformation (CCAM, CPAM), isolated lung has two major features: 1) the airway of the isolated lung does not communicate with the normal airway; 2) the blood supplying artery of the isolated lung comes from the body circulation rather than the pulmonary circulation, with branch arteries coming from the aorta being the most common. Isolated lung is divided into two types: intralobar and extralobar. Compared to CPAM, isolated lung is generally less prone to symptoms of compression of surrounding organs due to its excessive size; also, current studies have found that the incidence of cancer caused by isolated lung is very low, with only a very small number of reports. Therefore, the main effect of isolated lung on babies is the possibility of recurrent lung infections after birth. Also, there is some chance that isolated lung will resolve itself and the lesions will disappear before and after the baby is born. Therefore, parents whose babies are found to have isolated lung during pregnancy need not worry; the disease is benign and has limited impact on the baby, and the vast majority of children can be delivered normally without any problems. Evaluate asymptomatic at birth and wait until half a year to check enhanced CT to clarify the presence and nature of the lesion. For babies with surgical indications, minimally invasive thoracoscopic surgery is feasible to cure the disease by the age of 1 year.