Depending on the cause, oral medications and surgical treatments can be used to relieve the symptoms. Most of the burning sensation in the stomach is caused by chronic gastritis, gastric ulcer, gastric cancer and other diseases. 1. Chronic gastritis: some patients may manifest epigastric discomfort, fullness, dull pain, burning pain, lack of appetite, belching and other symptoms. Omeprazole, magnesium aluminum carbonate, bismuth potassium citrate and other drugs are often used. 2. Gastric ulcer: It may manifest as stomach pain, loss of appetite, postprandial bloating or stomach discomfort and other symptoms. It can be treated with drugs such as omeprazole, domperidone, etc. If there is Helicobacter pylori infection, it can be eradicated by using the quadruple method, i.e., one proton pump inhibitor such as omeprazole + one kind of bismuth such as colloidal bismuth + two kinds of antibiotics such as amoxicillin and clarithromycin. 3. Gastric cancer: there is no obvious symptom in the early stage, with the development of the disease, epigastric distension and pain, nausea, loss of appetite, belching, acid reflux, black stool and other symptoms may appear. Generally, surgery, chemotherapy, radiotherapy and biotargeting therapy are the main treatments. Burning sensation in the stomach suggests that the patient go to the hospital in time to improve the relevant examination, clarify the cause of the disease, and treat the cause.