The statement that “a high lupus anticoagulant means you have SLE” lacks a sound scientific basis and is not true. Lupus anticoagulant is essentially a kind of antiphospholipid antibody, and it is named “lupus anticoagulant” because this kind of antibody was first found in the blood of patients with SLE, and in fact, about half of patients with positive or elevated lupus anticoagulant are not suffering from SLE, so “high lupus anticoagulant means SLE” is not relevant. Therefore, there is no basis for saying that “a high lupus anticoagulant means you have SLE”. In addition to SLE, high lupus anticoagulant can also be seen in stillbirth, habitual abortion, arteriovenous embolism, etc. Therefore, patients with high lupus anticoagulant should further improve the antinuclear antibody profile, blood sedimentation rate, rheumatoid factor, antiphospholipid antibody and other related tests to clarify the cause of the abnormal laboratory test. Patients with high lupus anticoagulant are recommended to go to the rheumatology and immunology departments of regular hospitals for detailed consultation, to find out the cause and follow the doctor’s instructions for standardized treatment.