Chickenpox vaccine and hand, foot and mouth vaccine should not be given at the same time as far as possible, which may lead to superimposed adverse reactions after vaccination and aggravate the discomfort. Chickenpox vaccine is a type of live attenuated vaccine, which may cause heavier adverse reactions after vaccination. Hand, foot and mouth vaccine is usually an inactivated vaccine, and the adverse effects of this vaccine are relatively mild. Simultaneous administration of varicella vaccine and HFMD vaccine may result in a superimposition of adverse reactions after vaccination, and the body may experience fever, rash, dizziness, headache, diarrhea and other adverse reactions at the same time. Therefore, under the premise of time permitting, try not to receive two vaccines at the same time, although it will not affect the effect of the vaccine, but it will aggravate the body discomfort, try to receive two vaccines at an interval of 14 days.