The pain in the middle and upward inch of the breasts may be caused by trauma, pleurisy or coronary artery atherosclerosis. 1. Trauma: When the patient suffers a huge injury, resulting in sternum fracture, thus the symptoms of pain in the middle of the breasts one inch upward, usually accompanied by obvious breathing difficulties, activity limitation, localized swelling phenomenon. 2. Pleurisy: Pleurisy refers to the inflammation of the pleura caused by viral or bacterial pathogenic factors, which stimulate the pleura, and the patient will have chest pain, cough and chest tightness and other symptoms. 3. Coronary artery atherosclerosis: when the patient is stimulated by overwork and other triggers, the heart will have persistent contraction causing myocardial ischemia and hypoxia, which leads to radiating pain in the middle of the breasts up to one inch. When the patient appeared in the middle of the two breasts to the upper inch pain, should go to the hospital in time for chest CT examination, clear the cause of the disease and actively cooperate with the doctor’s treatment.