The best time for infants to take probiotics is in the morning, and it is recommended to take it before breakfast or with the same meal. In the morning, stomach acid is lower in the fasting state, which is conducive to the smooth arrival of probiotics to colonize the intestinal tract, help restore digestive function and establish normal intestinal flora. Although probiotics are not medicines, probiotic supplementation can treat pediatric diarrheal diseases, including indigestion, enteritis, dysentery and so on. Infants with normal body can not supplement probiotics, long-term supplementation may cause intestinal dysfunction. The best growth temperature of probiotics is 37℃, so the water temperature should be below 40℃, otherwise the water temperature is too low or too high, which can lead to low survival rate of probiotics and cannot achieve the proper effect. Each baby has individual differences, so it is recommended to supplement the probiotics needed under the guidance of a doctor when using probiotics. In addition, probiotics need to be kept refrigerated. If antibiotics are used at the same time, it is generally recommended to take probiotics 2 hours apart from the time of taking antibiotics.