Sinusitis with a blocked nose and difficulty breathing can be treated aggressively and symptomatically as prescribed by your doctor. Treatment methods include medication, surgery and some other methods to deal with. 1. Drug treatment (1) Intranasal decongestant treatment: it can effectively reduce the swelling of nasal cavity and sinus mucosa, so as to improve sinus drainage, commonly used drugs are furosemide nasal drops, seroquel nasal spray and so on. (2) Nasal glucocorticosteroid: it is the first choice of local drugs for the treatment of sinusitis, which can reduce the inflammatory reaction of the nasal mucosa, commonly used drugs are budesonide, mometasone furoate, etc., but we need to pay attention to the adverse effects of the drug, such as hemorrhage, bronchial spasm, cough and so on. (3) Mucolytic agents: such as commonly used standard myrtle oil, eucalyptus pinocarpine enteric soft capsule, etc., can effectively dilute nasal and sinus secretions, thus improving the activity of the nasal mucosal cilia, promote mucus discharge, and improve the nasal sinus blockage caused by dyspnea. 2. Surgical treatment: patients who are ineffective after standardized drug treatment and have anatomical abnormalities and intracranial complications can be considered for treatment by nasal endoscopic surgery. By correcting the anatomical abnormalities of the nasal cavity, removing irreversible lesions in the nasal cavity, and reconstructing the ventilation and drainage of the nasal cavity and sinuses, the symptoms of blockage and dyspnea can be relieved. 3. Other treatments: Nasal rinsing can help remove nasal secretions and improve the microenvironment of the nasal mucosa, thus relieving dyspnea caused by secretions blocking the nasal cavity. Commonly used rinsing solutions include saline, hypertonic saline and so on. After the onset of the disease, it is necessary to standardize the use of drugs and treatment after a systematic examination by a professional doctor for a clear diagnosis.