Abnormal liver function after chemotherapy for gastric cancer is usually caused by side effects after chemotherapy, which can be clarified by stopping or reducing chemotherapeutic drugs according to the situation, and using liver-protecting drugs at the same time, and further perfecting examination. Chemotherapy, as one of the important means of cancer treatment nowadays, has toxic side effects on normal cells besides killing tumor cells. There can be myelosuppression, gastrointestinal reaction, heart, liver and kidney toxicity, decreased immune function, hair loss and other immediate side effects, but also reproductive toxicity, second tumor and other long-term side effects. Silymarin can be consumed in mild and moderate hepatocellular injury with mild inflammation; glycyrrhizic acid preparations can be used in more severe inflammation to exert anti-hepatic inflammation by inhibiting the activity of phospholipase A2, such as glycyrrhizic acid monoammonium cysteine complex preparations. It is applied intravenously and also acts to neutralize the active oxides. Other commonly used drugs are bicyclic alcohol, polyene phosphatidylcholine and so on. Patients with abnormal liver function should pay attention to quit smoking and drinking, avoid using hepatotoxic drugs, pay attention to rest, can not be overworked, after chemotherapy should be regularly rechecked liver and kidney function, and active treatment. Please strictly follow the doctor’s instructions for drug treatment and do not use drugs on your own.