Progesterone on the 50th day of pregnancy is usually between 17.0-32.1ng/ml or between 52.7-101.1nmol/L. Progesterone is mainly secreted by the corpus luteum of the ovary in the early stages of pregnancy. Normal levels of progesterone help to maintain the endometrium in its normal form, which is more conducive to sustaining a pregnancy. If progesterone is low, it may lead to embryonic dysplasia and preeclampsia. At this time, the serum level of human chorionic gonadotropin should be checked to see if it is normal, and combined with the ultrasound results, individualized therapeutic measures should be formulated, such as oral progesterone capsule or intramuscular injection of progesterone injections to preserve the fetus. If progesterone is low, it may also be due to ectopic pregnancy, once diagnosed as ectopic pregnancy, timely termination of pregnancy is needed. If the progesterone is increased, generally caused by chorionic villus, chorionic epithelial cell carcinoma, corpus luteum cysts, essential hypertension, endocrine disorders and other disease factors, if the value of progesterone is only mildly high, it is recommended to adjust the diet, avoid soy products, progesterone-containing drugs. If the value of progesterone is obviously high, it is recommended to further check the hormone level and gynecological ultrasound under the guidance of the doctor, so as to clarify the cause of the disease and provide specific treatment.