At the request of our patients, we now list the treatments we generally use for premature ejaculation: Systematic desensitization-psychotherapy with no less than 30 min. per psychotherapy session, once a week for a total of 8 weeks. Before treatment, both husband and wife give their informed consent to cooperate with the treatment and sign an agreement. The content includes two aspects: (1) psychotherapy: first of all, to obtain trust, establish a close and trusting relationship, strengthen the education about sexual knowledge, for the patient depression and anxiety and other adverse emotions using hypnosis, suggestion techniques for guidance, comfort, support, encouragement and other psychological treatment measures. Help patients overcome psychological barriers and establish confidence. (2) Systematic desensitization behavior therapy: refer to Master & Johns’s sensate focus exercise[ and squeeze technique method: ① Non-genital sensual focus training: the couple concentrate on caressing body parts other than the sensual zone to eliminate the fear, anxiety and repression of sexual behavior, so that the couple establish confidence and intimacy, and naturally achieve sexual arousal. This process is treated for 1 week, during which no sexual intercourse is allowed. ②genital sensual concentration training: the couple will expand the scope of caresses to the sensual zone of both parties, this process treatment for 1 week. The effect of this squeeze is to inhibit the ejaculation reflex, which can sometimes cause penile weakness. This method is repeated 3 times and ejaculation is achieved on the 4th stimulation. This process is treated for 1 week, at least 2-3 times a week. ④ Heterosexual penis squeezing training: the above process is done by the heterosexual spouse ⑤ Vaginal accommodation and activity: starting from the female superior position with weak stimulation, gradually increase the intensity of stimulation in the form of stillness – shaking – turning – pumping, and when the patient has a sense of ejaculation urgency, slow down or stop the penis in the vagina When the ejaculatory urgency appears, slow down or stop the amplitude and frequency of penile pumping in the vagina and use some distracting verbal communication or other behaviors, if it cannot be relieved, immediately pull out and use the penile squeezing method, wait for the ejaculatory urge to subside and then restart a new round of penile pumping, and keep repeating this process 3 times before ejaculating for the 4th time, or later until both parties are satisfied. This process is treated for 4 weeks, at least 2-3 times a week.