Total knee replacement is a very efficacious procedure, but there are a number of risks that patients must be aware of prior to surgery. Life-threatening risks due to postoperative fat embolism or blood clots. 1. Post-operative infection. 2, Most of the patients of total knee replacement are elderly people, many of whom have geriatric diseases such as diabetes, heart disease, hypertension, etc. Improper preoperative bailout or postoperative treatment can induce the onset or aggravation of these diseases or lead to serious complications related to these diseases, causing harm to the patient. 3, total knee replacement of the elderly post-operative situation is more review, if there is no very mature, standardized response to a variety of unexpected security means, will also bring unnecessary risk to the patient. 4, Some doctors do not have much experience in surgery, and the number of surgical cases is not enough, resulting in the position of the intraoperative artificial joint is not ideal, laying a hidden danger for a possible second operation in the future early. 5.Lack of systematic and effective postoperative rehabilitation guidance, resulting in unsatisfactory postoperative functional recovery. However, all of the above risks are problems that can be well solved by a surgeon and team with a certain amount of experience in total knee replacement.