Genital herpes is a sexually transmitted disease caused by infection with the herpes simplex virus. The virus is found in the exudate of skin and mucous membrane damage, semen, prostatic fluid, cervical and vaginal secretions and can persist for a long time, and is transmitted mainly through sexual intercourse, causing primary genital herpes. The incubation period of herpes virus infection is 1 week to 2 months. It is difficult to cure and is prone to recurrence. The incubation period of primary genital herpes infection is about 3 to 5 days, and its onset is mostly regular: fever, headache, malaise are the common symptoms, which peak around 3 days after the appearance of local symptoms, accompanied by a local burning sensation, followed by erythema, and soon several small blisters or pustules distributed in clusters on the surface of the erythema, which break down to form vesicles and shallow ulcers, mostly with burning-like more intense pain, and most patients Most of the patients have burning pain and most of them have bilateral inguinal lymph node enlargement, and most of them can heal themselves in a week or so. In female patients, it occurs mostly on the labia, around the anus and vagina. In men, it occurs in the glans, coronal sulcus, urethra or penis, and can also be accompanied by a sore throat infection. Recurrent genital herpes tends to be milder and confined to the genitalia. The pathogenesis is that after the primary genital herpes has subsided after a week, the remaining herpes virus is latent in the sacral ganglion along the nerve axis via the peripheral nerves for a long time, and when the body’s resistance is reduced or certain stimulating factors such as fever, cold, infection, menstruation, gastrointestinal disorders, trauma, etc., the latent virus in the body can be activated and recur, which is the reason why genital herpes is prone to recurrence. Recurrence often occurs within 1-3 months after primary genital herpes, and about 60% of patients recur within 1 year after the first infection, some as many as 10 times or more, with symptoms milder than primary genital herpes. Infected individuals may still be infectious in the absence of symptoms and localized damage in between. Diagnosis relies on clinical symptoms and laboratory smear or pathogenic tests. PCR techniques have important clinical diagnostic value in the examination of secretions for pathogens. How to prevent? 1.First of all, understand the transmission route and disease characteristics of this disease, be clean, avoid unclean sexual contact, and advocate the use of condoms. 2, pay attention to self-protection in public places, especially for women, advocate shower, do not sit directly in public baths, swimming pools, seated toilets, etc. 3, pay attention to hygiene, pay attention to diligent change of underwear, do not use other people’s basin, swimsuit, towel, before going to the toilet must wash hands to prevent virus contamination. 4, the patient’s underwear, bed linen and its secretions contaminated utensils can be disinfected by boiling or disinfectant soaking method. During the active period of herpes, sexual intercourse is prohibited to avoid being infected by the virus. Because the parts not covered by condoms still have the possibility of spreading the virus. 5. If one of the partners is sick, the other partner should also go to the hospital for examination and treatment. Treatment 1. Avoid scratching to keep the herpes wall intact, clean and dry to prevent secondary bacterial infections. Use sensitive antibiotics when combined with bacterial infection. 2. Anti-viral treatment is the most commonly used method. Antiviral drugs such as acycloguanosine, acyclovir, famciclovir and vancomycin can shorten the disease process, prevent serious complications and prevent recurrence. 3, frequent relapses can be selected under the guidance of doctors long-term suppressive therapy.