Patients with uremia can wake up every day with particularly bitter mouth and bad breath symptoms, but there are more causes of bitter mouth and bad breath, and the specific causes need to be based on professional examination results, and cannot be generalized. Bitter mouth and bad breath may be caused by oral diseases, such as oral mucosal disease, gingivitis, dental caries or periodontitis, etc. Through good habits such as rinsing and brushing after meals, the symptoms of bad breath and bad breath can be gradually relieved. Bitter mouth and bad breath may also be caused by digestive system diseases, such as gastritis, gastric ulcer, cholecystitis, etc. Because the gastrointestinal tract is connected to the mouth, when the gastrointestinal tract is poorly digested, the food is fermented in the stomach, producing unpleasant gases such as sulfide, which reach the mouth and appear bad breath, and when saliva secretion is reduced, bitter mouth symptoms can appear. In addition, tonsillitis, pharyngitis, excessive smoking and alcohol abuse can cause bad breath and bitterness. If a patient has bad breath and bitterness, but also swelling of the face and lower limbs, weakness, loss of appetite, nausea and vomiting, and bleeding spots under the skin or mucous membranes, it may also be due to kidney failure or uremia. Patients with bitter mouth are recommended to go to gastroenterology or urology for relevant examinations to identify the specific causes and carry out symptomatic treatment. You should quit smoking and drinking, take rest, don’t stay up late and don’t get angry.