Individual variability exists, and there is no best-fit statement. Heart failure patients can take diuretics, ACEIs, ARBs, ARNIs, aldosterone receptor antagonists, beta-blockers, and so on. 1. Diuretics: such as Antibiotics, Hydrochlorothiazide, etc., reduce the cardiac load through diuresis and decrease the oxygen consumption of cardiomyocytes. 2. ACEI: such as enalapril, captopril, etc., through antagonizing the RAAS system, reduce the contractility of cardiomyocytes, reduce oxygen consumption, but also improve ventricular remodeling. 3. ARB class: such as valsartan, chlorosartan, etc., also by antagonizing the RAAS system, reducing cardiac oxygen consumption and improving ventricular remodeling. 4. ARNI: for angiotensin receptor enkephalinase inhibitors, representative drugs such as sacubitril valsartan, reduce cardiac myocyte oxygen consumption and improve ventricular remodeling. 5. Aldosterone receptor antagonists: such as spironolactone, aminopterin, etc., by antagonizing aldosterone, diuretic effect, reduce myocardial oxygen consumption. 6. β-receptor blockade: such as propranolol, betalactam, etc., blocking β-receptors, can reduce myocardial oxygen consumption, improve ventricular remodeling. You can also take some drugs such as nitrates (nitroglycerin), positive inotropic drugs (levosimendan) and so on. Each kind of drug has corresponding contraindications, and should be used under the guidance of the doctor, not to take the drug treatment on their own.