A positive H. pylori is contagious, and currently the national legal infectious diseases are categories A, B, and C. Although H. pylori is not included in the statutory infectious diseases, it has been found that H. pylori can indeed be transmitted from person to person. The clinical evidence is not yet strong as to whether H. pylori can be transmitted between animals and humans. Therefore, human-to-human transmission is the only way H. pylori can be transmitted. Therefore, it is important to develop good lifestyle habits during work or diet, such as washing hands before and after meals, which can reduce fecal-oral transmission to some extent. Also in clinical work, we found that there is a family gathering phenomenon, which is mostly caused by fecal-oral or oral-oral transmission. Therefore, we advocate meal sharing rather than meal gathering, and the living environment, such as water management, requires national efforts to improve the level of people’s health and economic conditions, thus reducing fecal-oral, oral-oral, and gastro-oral transmission, and reducing Hp infection.