ST-T changes are not necessarily a sign of major disease, and in general, ST-T changes mean that the patient has myocardial ischemia. ST-T changes are a common clinical manifestation of ECG. ST-T changes include i.e. ST-T wave elevation, ST-T lowering or inversion. ST-T changes are commonly seen in major diseases such as acute myocardial infarction, but also in hypertensive heart disease, coronary artery disease, pulmonary artery disease, acute pulmonary embolism, cardiomyopathy and other diseases. In addition, they may also result from abnormal autonomic regulation. Therefore, when ST-T changes occur, you should go to a regular hospital in time to clarify the cause of the disease and follow the doctor’s instructions for treatment.