Discomfort in the middle of the back can be caused by the following diseases: first, periarthritis of the shoulder, which can also cause shoulder discomfort and aggravation of symptoms after activity, and is associated with chronic strain over a long period of time, especially in the elderly. In addition, chronic injury or shoulder surgery, as well as localized fasciitis, can also cause pain. Second, patients with chest or tumor diseases, including neurofibromas, may also experience chest pain, back pain, and discomfort, which can be confirmed by CT examinations and, if necessary, surgery. Third, there are also patients with subcutaneous lesions, including subcutaneous lipomas and fibroids, which may also show symptoms of discomfort and be accompanied by pain. If necessary, surgical treatment is required to remove the lesion, and postoperative pathological examination is also required.