Muscle atrophy in the legs due to osteophytes may be caused by pain during activities or dysfunction due to deformity of joints, etc. Treatment mainly includes conservative treatment and surgery. 1. Conservative treatment: For patients with muscle atrophy due to pain during activities, anti-inflammatory drugs such as ibuprofen can be taken orally to relieve the pain; heat therapy, massage, electrical stimulation therapy, rehabilitation training and other methods can be chosen to restore the normal strength of the muscles as well as the mobility of the joints. The above medications should be used under doctor’s guidance to avoid self-medication. 2. Surgery: Surgery can also be performed for patients with atrophy of large and small leg muscles caused by joint deformity due to osteomalacia. Surgical methods include arthroscopic cleanup, joint replacement and so on. The purpose of surgery is to restore normal joint function, and the specific surgical method needs to be decided according to the doctor’s assessment of the patient’s own condition. After surgery, strength training is performed to restore muscle circumference. If the symptoms of muscle atrophy in the legs are serious, the patient should go to the hospital in time for treatment and should not blindly use medication.