Whether you can stop taking metformin and gliclazide after three years should be decided after evaluating your condition under a doctor’s supervision, and it is not recommended to stop taking the drug if your blood sugar is not well controlled. Metformin and gliclazide are both hypoglycemic drugs, and the combination is used in cases where monotherapy is not effective. Diabetic patients combined use of metformin and gliclazide for three years, if the blood sugar control is stable, need to be agreed by the doctor, assessment of pancreatic islet function and then adjust the medication, the patient can not stop the medication on their own, because stopping the medication may lead to an increase in blood sugar. It is recommended that patients adjust the medication under the guidance of a doctor and not on their own.