Antihypertensive treatment requires regular medication, but many hypertensive patients do not know that this is very important, often forget to take the medication, when remembered to make up a piece; some hypertensive patients as long as they are not comfortable to just find some antihypertensive drugs to eat, there are also some patients because the morning to draw blood tests, do not eat antihypertensive drugs. These practices are both unscientific and unsafe. Experts point out that the antihypertensive drugs are taken at some time to have a good effect. So, how exactly should hypertensive patients take their medication correctly? The typical blood pressure fluctuation pattern of hypertension appears in the day two peaks, respectively, at 9-11 a.m. and 6-7 p.m., after which it begins to slowly decline to a better low at 2-3 a.m. the next day. Generally antihypertensive drugs reach a better high blood pressure concentration 2-3 hours after taking the drug. To keep blood pressure stable throughout the day, if you are taking a 24-hour long-acting formulation, it is sufficient to take one tablet in the morning after waking up. If it is a short-acting preparation, you can take it in the morning after waking up; it is better to take the last dose of the day around 6:00 p.m., so that the blood pressure concentration of the antihypertensive drug can better match with the peak of blood pressure. Taking medication too late can lead to low perfusion of important organs at night, which is especially bad for the elderly and can easily trigger a brain attack. Improper administration of medication, as in the case of the previous patients, and poor control of high and low blood pressure can cause even more damage to the organs. Therefore, long-acting antihypertensive drugs, such as amlodipine, benazepril and coxsartan, should be taken once a day at 7:00 a.m., so that blood pressure can be maintained more effectively. Some antihypertensive drugs are recommended to be taken with food to increase drug absorption. For example, metoprolol can increase its bioavailability by 40% when taken with a meal. Some drugs are better taken 1 hour before meals and on an empty stomach, such as captopril, because food can reduce its absorption by 30%-40%.