Dead skin on the hands may be due to exfoliative keratolysis, tinea versicolor or chronic eczema, it is recommended that the patient under the guidance of a doctor to clarify the specific cause of the disease and then symptomatic treatment. 1. Exfoliative Keratolysis: Exfoliative Keratolysis can be caused by sweaty hands or emotional stimulation. Treatment can be topical moisturizers, keratin softeners, or even exfoliators, such as urea cream, to improve the symptoms. 2. Ringworm: ringworm is caused by fungal infection, can be developed from tinea pedis, in the treatment can be used externally anti-fungal cream, such as terbinafine cream, naftifine ketocon cream, etc., if necessary, need to follow the doctor’s prescription oral antifungal drugs. 3. Chronic eczema: for patients with chronic eczema in the hands can be repeated dead skin, patients can use glucocorticoid ointment to improve the symptoms, such as clobetasol propionate ointment, etc., if necessary, can be partially sealed package treatment. It is recommended that patients with dead skin on their hands go to the hospital in time for a clear diagnosis, and actively use medication under the guidance of the doctor.