The onset of schizophrenia is definitely related to genetic factors, as illustrated by a few figures: the prevalence of the disease in children is 40% for both parents with the disease, 16% for one parent with the disease, 6 times higher than normal in the next generation for people with a family history of the disease, and 0.6% for people without a family history of the disease (i.e., the general population). Human heredity (children look like their parents) is passed on through genes, and families are genetically similar, but each individual has some variation, which can explain why some children have a disease while others do not, despite one parent having the disease. The closer the blood relationship, the greater the similarity, and vice versa, the smaller. This could explain that the closer the blood relationship is, the greater the chance of having the same disease, and the more distant the chance is, the less. Some family members say that he got the disease after the birth of a child, with the implication that it will not be passed on to the child, but the actual human genes do not become available during the lifetime, so there is the same possibility of inheritance. Since the genetic variation of schizophrenia is still in the research stage and has not yet been used clinically, it is not possible to determine the likelihood of the next generation of high-risk people having the disease through premarital testing (by examining its genetic variation). It can only be estimated by the statistical probabilities that are now available. The existing legal knowledge states that mentally ill people cannot marry during their illness, and who in fact is likely to marry during their illness? Some people ask, “My sister is mentally ill, if I have a child will I also get the disease. If we use the above figure set, the prevalence of the disease in normal people is 0.6%, and with a genetic history, it is 6 times higher, which is 3.6%. It is up to you to decide whether you want to have a child or not.