Some questions about chemotherapy for ovarian cancer (III)

  14. Is it possible to take some Chinese medicine during chemotherapy?  You can take some Chinese herbal medicines during chemotherapy, but you should pay attention to the right amount, because chemotherapy drugs need to be metabolized by liver and kidney, so taking too much of them will increase the burden of liver and kidney, which may cause abnormal liver and kidney function and cause chemotherapy not to be carried out on time. Yuan Guangwen, Department of Gynecology, Cancer Hospital, Chinese Academy of Medical Sciences 15. How to choose chemotherapy regimen after recurrence of ovarian cancer?  Recurrent ovarian cancer is divided into drug-resistant recurrence and sensitive recurrence. The way to judge is the interval between the time of last chemotherapy and the time when recurrence is found. Patients with sensitive relapse can continue to choose first-line chemotherapy regimens or other regimens for ovarian cancer, while patients with drug-resistant relapse need to choose second-line chemotherapy regimens for ovarian cancer.  What is second-line chemotherapy?  Second-line regimens are chemotherapy regimens that have been clinically studied and proven to be effective for patients with resistant ovarian cancer. The second-line chemotherapy drugs for ovarian cancer include: liposomal adriamycin, docetaxel, gemcitabine, topotecan, platinum oxalate, nedaplatin, etoposide, pemetrexed, isocyclophosphamide, and so on.  17. What is the effectiveness of second-line chemotherapy regimens?  Since patients receiving second-line chemotherapy regimens are those who are resistant to first-line regimens, the efficiency rate of second-line regimens is lower, generally between 10% and 30%.  18. What is chemoresistance?  Chemoresistance means that the tumor continues to grow after chemotherapy, or new metastases appear, and the chemotherapy drugs are ineffective against such tumor.  19. What should patients pay attention to when infusing different chemotherapy drugs?  When infusing chemotherapy drugs, patients should pay attention to prevent the drugs from leaking outside the blood vessels, preferably by deep vein placement (such as subclavian vein puncture or PICC placement) to prevent drug leakage. Since most chemotherapeutic drugs are metabolized by the liver and kidneys, attention should be paid to drinking more water and taking oral hepatoprotective drugs during chemotherapy. In addition, attention should be paid to enhancing nutrition and vitamin supplementation to reduce chemotherapy-related side effects. Finally, it should be noted that there are some special requirements for individual drug infusion, which should be communicated with the doctor in time.