Every year, April 11 is World Parkinson’s Day, in fact, many people feel that Parkinson’s disease is very far away from us, for a normal person, shopping and walking is no ordinary thing, but for patients suffering from this disease is a very difficult thing, this disease is second only to tumors and cardiovascular disease for patients’ ability to live their daily lives, has become the number three killer of the elderly. So what are the clinical manifestations of Parkinson’s disease? What is the best treatment and measures? 1, first of all, we first understand what is Parkinson’s disease? Parkinson’s disease, also known as tremor paralysis, is a common neurodegenerative disease of the middle-aged and elderly, second only to tumors and cardiovascular diseases that seriously endanger the health of the elderly and disabling diseases. It was first described in 1817 by a British doctor named James Parkinson. Parkinson’s disease was first described by a British doctor named James Parkinson in 1817, and later people called the disease Parkinson’s disease in honor of this doctor. The pathogenesis of Parkinson’s disease is mainly due to the pathological change of cells in the substantia nigra of the midbrain, which reduces the synthesis of a neuromediator called dopamine, which cannot maintain the normal work of the regulatory motor nerves, resulting in a series of symptoms of movement disorders, such as involuntary tremor of the head and neck of the limbs at rest, muscle stiffness, motor retardation, postural balance disorders, etc., resulting in the patient’s inability to take care of himself, which seriously affects the patient’s The quality of life is seriously affected. Therefore, in common parlance, Parkinson’s disease is “the disease that makes you unable to move”, known as the “third killer” of the middle-aged and elderly. 2. What is the incidence of Parkinson’s disease in China? Parkinson’s disease is a relatively uncommon disease that affects middle-aged and elderly people. At present, the incidence of Parkinson’s disease in China is similar to that of developed countries in the world. According to the results of a survey conducted by the Chinese Society for Rheumatology, the incidence of Parkinson’s disease is about 1 in 1,000 among people over 55 years old, and after 65 years old, it may reach 2 to 3 in 1,000, which means that there are about 2 million Parkinson’s patients in China. The number of Parkinson’s disease patients will increase year by year. In addition, the incidence of male patients is higher, so the number of male patients will be relatively more, men than women may be more than double, so for these middle-aged and elderly male comrades, if tremor, or muscle stiffness, or inflexible movements, we should be vigilant and go to a specialist hospital early. 3, Parkinson’s disease is mainly seen in the middle-aged and elderly people over 50 years old, is not the young people will certainly not get? That is not necessarily true, we say that the elderly are more prevalent, does not mean that young people must not get this disease, especially in recent years, Parkinson’s disease in young people is also on the increase, the smallest seen clinically may be 30 to 40 years old Parkinson’s disease, I have an elementary school classmate love only 48 years old this year, 3 years ago was diagnosed with Parkinson’s disease, this is called young Parkinson’s disease, but compared to the elderly The incidence of Parkinson’s disease is very low compared to that of older people. There is also a situation where some young people or middle-aged or elderly people can get a patient with symptoms similar to those of Parkinson’s disease, but they are often secondary to inflammation, poisoning, drug toxicity, etc. This may not necessarily be true Parkinson’s disease, but its manifestations may be similar to the symptoms of Parkinson’s disease, which we call Parkinson’s syndrome, which is not true Parkinson’s disease, which should be distinguished, because the difference between them Treatment methods and prognosis are different between them. 4.What are the causes of Parkinson’s disease? What habits or factors may be associated with it in daily life? In general, the causes of Parkinson’s disease are not fully understood. However, some risk factors are related to the development of Parkinson’s disease, such as dietary habits, for example, the incidence of Parkinson’s disease is higher in people who lack fruits and dairy products for a long time. In addition, environmental factors, such as frequent exposure to toxic gases, or heavy metals, or strong environmental pollution, these also have the potential to promote the onset of Parkinson’s disease. The incidence of Parkinson’s disease in the family is three times higher in people with a parent or sibling with Parkinson’s disease than in the normal population. People exposed to herbicides and pesticides have a higher risk of developing the disease than other people. So the cause of Parkinson’s disease is related to ageing, environmental factors, genetic factors, etc. It is difficult to explain with a single factor. 5, then where is the danger of Parkinson’s disease focus? Because Parkinson’s disease with the current level of technology, once suffering from it, there is no way to cure it, the disease is slowly progressing, as the age of its symptoms will slowly worsen. Although there are many medications and surgical treatments available, they do not stop the progression of the disease, so the disease is lifelong. In severe cases, it can lead to disability and loss of the ability to take care of oneself, and the psychological pressure on the patient and the family is very great. Of course, more than anything else, it brings patients inconvenience in life and work, as well as a lot of physical and psychological unpleasantness, or painful feelings. 6.Since Parkinson’s disease is so harmful, what good treatment methods are available? For the treatment of Parkinson’s disease, there are four main categories, one is drugs, one is surgery, the third is functional rehabilitation therapy, including massage, hydrotherapy, exercise, psychotherapy, rational diet and other comprehensive treatment, and the fourth is other types of methods such as stem cell therapy or gene therapy. At present, it is believed that once Parkinson’s disease is developed, patients need to take medication for life, especially for early stage patients. Some patients can undergo brain surgery at the appropriate time when medication is not effective. At the same time, the care of family members, early standardized rehabilitation, reasonable diet and psychotherapy are also crucial to improve the quality of life of patients. With reasonable and individualized treatment, most patients’ symptoms can be well controlled and some patients can maintain better function for 15-20 years. It should be emphasized that since there are no specific drugs for Parkinson’s disease in the world, early detection, early diagnosis and early treatment are necessary to benefit patients. 7.When it comes to early treatment, we also think of early detection. How can we find out early that we have Parkinson’s? Can you teach us some diagnostic tips? Early diagnosis of Parkinson’s disease is really an important issue, because if it can be diagnosed early, even before symptoms appear, then intervention will be a boon to Parkinson’s patients. Unfortunately, we do not yet have a way to diagnose patients at an early stage, but only as early as possible. Many patients are unaware of the symptoms and are not diagnosed according to our current level of diagnosis, which is not good if they are delayed for a long time. Some recent studies have shown that the loss of sense of smell in middle-aged and elderly people is often a sign of Parkinson’s disease in its early stages. There is also inflexibility of the hands and feet, abnormal sensation, numbness, aching, neck pain, etc., and also misdiagnosed as cervical spondylosis, with such signs should consider the possibility of Parkinson’s, you can look for neurology or Parkinson’s specialist. 8. We have talked about a lot of general knowledge about Parkinson’s disease, but is there anything you would like to tell Parkinson’s patients and their families? At present, Parkinson’s disease is a common disease that occurs in middle-aged and elderly people. According to the current incidence rate, in the future society, there may be one Parkinson’s patient in every four families, and with the arrival of an aging society, there will be more and more such diseases. It is no longer a rare disease, it concerns the vital interests of each and every one of us. Now we have many means to help Parkinson’s patients overcome their psychological and physical pain, and through reasonable treatment, many patients can return to society and enjoy the happiness of their old age. The key is that the patients themselves should have a good attitude, do not think that this disease can not be cured, in fact, it is the same as many diseases, such as diabetes, hypertension, these diseases are also incurable, there is no difference. Therefore this disease is not terrible, first of all, you should accept it psychologically, and then treat it reasonably, follow medical advice, and visit the hospital regularly. Many patients who have this disease always think to cure, to many places to inquire about the so-called “ancestral secret recipes”, and strange prescriptions, etc., with this mentality will fall for. Now the search engine as long as you give money to rank in front, so search out a lot are not now the regular treatment of drugs, many are prescriptions, these prescriptions are often fraudulent. This aspect we must pay attention to, when you come across a new treatment out, must go to consult the regular medical institutions, do not be deceived. Because Parkinson’s disease itself is very costly, if you then put money into something as useless as buying a prescription, it’s like throwing money away and will only add insult to injury. I hope that the majority of patients and family members with a positive attitude, out of the family, into the community, and actively participate in public welfare activities, and actively work. There is no need to give up your beloved work and seek medical treatment everywhere in the south and north, which is unnecessary. At the same time the national neurologist on Parkinson’s disease treatment technology improvement, our country’s treatment level should be synchronized with the world, so patients can enjoy the latest achievements of today’s technology through the regular network, regular medical institutions.