Sensitive skin with blackheads is related to excessive sebaceous gland secretion, Propionibacterium acnes infection, abnormal keratinization of follicular sebaceous gland ducts, etc., and should be removed according to the different causes of the disease by choosing medication, physical therapy and other methods. 1. For those caused by excessive sebaceous gland secretion, topical retinoic acid ointment or oral isotretinoin can be used to inhibit sebaceous gland secretion. 2. For those caused by Propionibacterium acnes, benzoyl peroxide or azelaic acid can be used externally to inhibit Propionibacterium acnes as prescribed by the doctor; blue light irradiation can kill Propionibacterium acnes. 3. For those caused by abnormal keratinization of follicular sebaceous gland ducts, topical retinoic acid or oral isotretinoin can be used as prescribed by the doctor; photodynamic therapy can improve the keratinization of sebaceous gland ducts. It is recommended that patients go to the hospital in a timely manner, to clarify the cause of the disease, and standardized treatment under the guidance of the doctor.